tag:blogger.com,1999:blog-11034229.post8611964983591180268..comments2023-07-14T02:53:40.719-07:00Comments on retired doc's thoughts: Everybody knows that thiazides are clearly the best anti-hypertensive. On the other hand..james gaultehttp://www.blogger.com/profile/05537303135780186926noreply@blogger.comBlogger3125tag:blogger.com,1999:blog-11034229.post-48829992145300610332011-01-31T13:14:11.312-08:002011-01-31T13:14:11.312-08:00Well, I would not want to argue with expert opini...Well, I would not want to argue with expert opinion and anecdotal experience.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-11034229.post-85720953924855373162011-01-30T14:33:03.004-08:002011-01-30T14:33:03.004-08:00The hypertension experts I know specifically prais...The hypertension experts I know specifically praise chlorthalidone over hctz. We have probably all made the mistake of equating the chlorthalidone data with hctz substitution.<br /><br />Perhaps a thiazide (chlorthalidone) is a great first line drug. Our anecdotal experience supports this reasoning.rcentorhttps://www.blogger.com/profile/07717424591748588051noreply@blogger.comtag:blogger.com,1999:blog-11034229.post-5631215934312762282011-01-27T08:56:00.318-08:002011-01-27T08:56:00.318-08:00Ah, Dr. Gaulte! But thiazides ARE the first-line ...Ah, Dr. Gaulte! But thiazides ARE the first-line drug to use in EVERY case of hypertension. Why? Because they're dirt cheap. Just like sulfonylureas should ALWAYS be used as the first line drug in Type II diabetes. It doesn't matter that they're not islet sparing and more physiologically sophisticated alternatives may be available. Cheapness trumps all. Guidelines and formularies say it does.Doug Perednia, MDhttp://www.roadtohellth.comnoreply@blogger.com